ICBEM - Program Agenda

INTERNATIONAL

CONFERENCE on

BRAIN

ENERGY

METABOLISM

16TH INTERNATIONAL CONFERENCE ON BRAIN ENERGY METABOLISM (ICBEM):

PRESERVING CELLULAR ENERGETICS AND BRAIN FUNCTION IN AGING AND NEUROLOGICAL DISEASE

*=Early Career speakers

MONDAY, JUNE 29

12:00 - 16:00	ICBEM Registration Desk Open / poster mounting
16:00 - 16:30	WELCOME & ANNOUNCEMENTS Chairs: Jordi Duran, PhD & Joao Duarte, PhD Welcome & Acknowledgements from the Program Committee Information about ISN Information about ISCBFM Welcome from the Organizing Committee & Presentation of the Safety Plan
16:30 - 17:30	PLENARY LECTURE: Effects of metabolism in pericytes on cerebral blood flow in normal and aging brain Thomas Longden, PhD, University of Maryland
17:30 - 18:00	POSTER BLITZ I: Presentations of student and postdoc posters (1 slide; 1 min) Chairs: Joao Duarte, PhD & Blanca Aldana, PhD
18:00 - 20:30	WELCOME RECEPTION & DINNER

TUESDAY, JUNE 30

8:30	ICBEM Registration Desk Open / poster mounting
9:00 - 10:30	SYMPOSIUM 1: Brain Drain: Unclogging the Mysteries of Neurovascular Coupling Chairs: Gary Yellen, PhD/student or postdoc TBD Oxygenation of blood with functional activation - Sava Sakazdik, PhD, Harvard University Cerebrovascular endothelial cell mitochondrial dysfunction in Alzheimer's disease - Rebecca Parodi-Rullán, PhD, Temple University Pericyte remodeling is deficient in the aged brain and contributes to impaired capillary flow and structure - Andy Shih, PhD, Seattle Children's Hospital
10:30 - 11:00	Refreshment break & Poster viewing
10:30 - 12:00	SYMPOSIUM 2: Travel Awardee Short Talks (9 speakers, 7 min talks + 3 min discussion) Chairs: Joao Duarte, PhD/Maite Solas, PhD
12:00 - 12:30	POSTER BLITZ II: Presentations of student and postdoc posters (1 slide; 1 min) Chairs: Kelly Drew, PhD & student or postdoc TBD
12:30 - 14:00	Lunch Break
14:00 - 15:30	SYMPOSIUM 3: The Unexpected roles of neuronal glycolysis in normal and aging brain Aberrant upregulation of glycolysis mediates a neurodegenerative disorder - Marina Garcia Macia, PhD, University de Salamanca Glycolytic shifts in neurodegeneration and aging - Ken Nakamura, PhD, Gladstone Institute/UCSF Compensatory activity of the PC-ME1 metabolic axis underlies differential sensitivity to mitochondrial complex I inhibition in astrocytes and neurons - Eduardo Balsa, PhD, Universidad Autonoma de Madrid
15:30 - 17:30	POSTER SESSION 1

WEDNESDAY, JULY 1

8:30	ICBEM Registration Desk Open / poster mounting
9:00 - 10:30	SYMPOSIUM 4: Lipid metabolism and alterations in aging brain Chairs: Maria Ioannou, PhD/student or postdoc TBD Loss of FA degradation by astrocytes mitochondria triggers inflammation and neurodegeneration - Fei Yin, PhD Neuron-glia lipids metabolic cycle couples sleep to mitochondrial function - Amita Sehgal, PhD Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging - Jessica Ellis, PhD
10:30 - 12:30	POSTER SESSION 2
12:30 - 14:00	Lunch Break
14:00 - 15:30	SYMPOSIUM 5: Microglial metabolism: Fueling the fire or fighting it? Chairs: Ray Swanson, MD /student or postdoc TBD Hexokinase 2 and glycolysis in microglial activation - Gary Landreth, PhD Complex 1 sustains microglial activity in inflammation - Stefano Pluchino, PhD Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity - Zhihua Guo, PhD
15:30 - 15:45	Quick break
15:45 - 17:15	INTERACTIVE DISCUSSION: Roundtable discussion about microglial metabolism Chair: Ray Swanson, MD
17:15 - 18:45	EARLY CAREER MENTORING with established investigators for students, postdocs and early career investigators
	Dinner on your own

THURSDAY, JULY 2

8:30	ICBEM Registration Desk Open
9:00 - 10:30	SYMPOSIUM 6: Ketones: novel roles for brain’s alternative substrates Chairs: Carlos Diaz-Garcia, PhD/student or postdoc TBD The impact of mild episodic ketosis on microglia and hippocampal LTD in 5xFAD mice - Izume Maezawa, PhD Ketogenic β-hydroxybutyrate regulates β-hydroxybutyrylation of TCA cycle-associated enzymes and attenuates disease-associated pathologies in Alzheimer's mice - Zhangxiang Wang, PhD β-hydroxybutyrate regulates proteostasis in the aged and Alzheimer’s disease brain - Josh Newman, PhD
10:30 - 11:00	Refreshment Break & Poster viewing
11:00 - 12:30	SMALL GROUP DISCUSSIONS: Topics suggested from the attendees
12:30 - 14:00	Lunch Break
14:00 - 16:10	SYMPOSIUM 7: The Glia-Neuron Gossip: Secrets of Cellular Communication Chairs: Maya Kaelberer, PhD/student or postdoc TBD Metabolic interactions between astroglial CB1R receptors, the lactate receptor HCA1R and serine: Who’s in control? - Ignacio Fernandez-Moncada, PhD Abeta increases astrocyte IDO1 to restore lactate production - Katrin Andreasson, PhD [10 minute break] Adenosine signaling to astrocytes coordinates brain metabolism and function - Alexander Gourine, PhD Effects of ApoE on fatty acid trafficking to lipid droplets in astrocytes - Maria Ioannou, PhD
16:10 - 16:40	Refreshment Break & Poster viewing
16:40 - 17:40	SYMPOSIUM 8: Targeting bioenergetics in the aging neuron Chairs: Robert Zorec, PhD/student or postdoc TBD APOE4 exacerbates plaque-induced microglial reactivity and lipid metabolism - Lance Johnson, PhD, University of Kentucky Neurovascular function in mouse models of mixed disease (AD and atherosclerosis) - Clare Horwath, PhD
17:50 - 18:30	SYMPOSIUM 9: Interactive Discussion on key and/or emerging areas that need more research Facilitators: Ray Swanson, Lindy Rae, and Joao Duarte
18:30 - 19:00	SPECIAL SESSION Presentation of awards for best student short talks and student/postdoc posters - Chair: Mary McKenna, PhD Meeting wrap up & closing comments - Jordi Duran, PhD
19:00 - 22:00	CLOSING DINNER

FRIDAY, JULY 3

7:00 - 8:00 AM Breakfast at your hotel

8:00 - 5:00 PM ONE-ON-ONE NETWORKING OPPORTUNITIES

These optional informal networking events offer young scientists the opportunity to engage in discussions and consultations with senior scientists and other meeting participants. It's a chance to discuss their research, explore potential collaborations, or seek advice from more experienced scientists.

Special Thanks to our 2024 Sponsors

ICBEM is a registered FL non-profit organization.

©ICBEM 2023

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