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INTERNATIONAL

CONFERENCE on

BRAIN

ENERGY

METABOLISM

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Special Thanks to our 2026 Sponsors

         

MONDAY, JUNE 29                                                                                                    *=Early Career speakers

 14:00 - 18:00 ICBEM Registration Desk Open / poster mounting  
 16:00 - 16:30

WELCOME & ANNOUNCEMENTS

Chairs: Jordi Duran, PhD & Joao Duarte, PhD

  • Welcome & Acknowledgements from the Program Committee 
  • Information about ISN 
  • Information about ISCBFM 
  • Welcome from the Organizing Committee & Presentation of the Safety Plan
  
 16:30 - 17:30

PLENARY LECTURE: 

Effects of Metabolism in Pericytes on Cerebral Blood Flow in Normal and Aging Brain

Thomas Longden, PhD, University of Maryland

  
 17:30 - 18:00 POSTER BLITZ I: Presentations of student and postdoc posters (25 pitches; 1 slide/1 min)

Chairs: Joao Duarte, PhD & Caroline Lindy Rae, PhD

  
 18:00 - 20:30 WELCOME RECEPTION & DINNER   

TUESDAY, JUNE 30

 8:30  ICBEM Registration Desk Open / poster mounting  
 9:00 - 10:30 SYMPOSIUM 1: Brain Drain: Unclogging the Mysteries of Neurovascular Coupling

Chairs: Gary Yellen, PhD & Chloe Lucido, student

  • Oxygenation of blood with functional activation - Sava Sakazdik, PhD, Harvard University
  • Cerebrovascular endothelial cell mitochondrial dysfunction in Alzheimer's disease - Rebecca Parodi-Rullán, PhD, University of Puerto Rico
  • Unique interactions between perivascular fibroblasts and macrophages in cerebrovascular homeostasis - Stephanie Bonney, PhD, CU Anschutz
  
 10:30 - 11:00 Refreshment Break & Poster Viewing  

 11:00 - 12:30

 SYMPOSIUM 2: Short Talks (9 speakers, 7 min talks + 3 min discussion)

Chairs: Joao Duarte, PhD & Maite Solas, PhD

  1. Investigating altered glycolysis at the synapse in the context of TDP-43 proteinopathies – Sara Langberg, Penn State College of Medicine
  2. Defining cell-specific and spatially resolved cerebral metabolic profiles across the lifespan using targeted, high-resolution spatial transcriptomics – Chloe Lucido, University of Kentucky
  3. Astrocytic sulfite oxidase participates in mitochondrial electron transport and hypoxic NO production via ROS scavenging and nitrite reduction – Alexander Mascarenas, University College of London
  4. Ketogenic diets partially restore bioenergetic pathways in the hippocampus of an Alzheimer’s disease mouse model – Isaura Maria Suarez Uribe, Université de Sherbrooke
  5. β-Adrenergic and activity-dependent regulation of neuronal hormone-sensitive lipase – Annelise Francisco, Lund University
  6. Bioenergetic of determinants of cofilactin rod formation in hypoxic and excitotoxic neurite injury – Nguyen Mai, University of California, San Francisco
  7. Mapping mitochondrial membrane potential and metabolic coupling in neurons – Elena Morin, University of Rochester
  8. Transcriptional and neuroprotective effects of hexokinase-2 inhibitors administered after stroke – Gokhan Uruk, University of California San Francisco and San Francisco Veterans Affairs Medical Center
  
 12:30 - 14:00 Lunch Break  
 14:00 - 14:30 POSTER BLITZ II: Presentations of student and postdoc posters (1 slide; 1 min)

Chairs: Kelly Drew, PhD & student or postdoc TBD

      • Coming soon
  
 14:30 - 16:00

SYMPOSIUM 3: The Unexpected Roles of Neuronal Glycolysis in Normal and Aging Brain

Chairs: Doug Rothman, PhD & Sara Langberg, student

  • Inorganic phosphate and the rapid mobilization of metabolic energy in neurons - Gary Yellen, PhD, Harvard Medical School
  • Aberrant upregulation of glycolysis mediates a neurodegenerative disorder - Marina Garcia Macia, PhD, University de Salamanca
  • Glycolytic shifts in neurodegeneration and aging -  Ken Nakamura, PhD, Gladstone Institute/UCSF
  
 16:00 - 18:00 POSTER SESSION 1   

    WEDNESDAY, JULY 1

     8:30 ICBEM Registration Desk Open / poster mounting  
     9:00 - 10:30

    SYMPOSIUM 4: Lipid Metabolism and Alterations in Aging Brain

    Chairs: Maria Ioannou & PhD & Annelise Francisco, postdoc

    • Loss of FA degradation by astrocytes mitochondria triggers inflammation and neurodegeneration - Fei Yin, PhD, University of Arizona
    • Neuron-glia lipids metabolic cycle couples sleep to mitochondrial function - Amita Sehgal, PhD, University of Pennsylvania
    • Acyl-CoA synthetase 6 is required for brain docosahexaenoic acid retention and neuroprotection during aging -Jessica Ellis, PhD, Wake Forest University
    		  
     10:30 - 12:30 POSTER SESSION 2  
     12:30 - 14:00 Lunch Break  
     14:00 - 15:30

    SYMPOSIUM 5: Microglial Metabolism: Fueling the Fire or Fighting It?

    Chairs: Ray Swanson, MD & Nicholas Gabriel Gonzalez Perez, student

    • Dual roles of hexokinase 2 in shaping microglial function by gating glycolytic flux and mitochondrial activity - Zhihua Gao, PhD, University of Alberta

    • Complex 1 sustains microglial activity in inflammation - Luca Peruzzottti-Jametti, MD, PhD, University of Cambridge

    • APOE4 exacerbates plaque-induced microglial reactivity and lipid metabolism - Lance Johnson, PhD, University of Kentucky
    		  
     15:30 - 15:45 Quick Break  
     15:45 - 17:15

    INTERACTIVE DISCUSSION: Roundtable Discussion on Microglial Metabolism

    Chairs: Ray Swanson, MD

    		  
     17:15 - 18:45 EARLY CAREER MENTORING

    with established investigators for students, postdocs and early career investigators

    Chairs: Kelly Drew, Caroline Lindy Rae, Gary Yellen, Susana Scafidi

    		  

    THURSDAY, JULY 2

     8:30 ICBEM Registration Desk Open
    		  
     9:00 - 10:30

    SYMPOSIUM 6: Ketones, MCTs and Fatty Acids: Novel Roles for Brain’s Alternative Substrates

    Chairs: Carlos Diaz-Garcia, PhD & Leigh-Ana Rossitto, student

    • β-hydroxybutyrate regulates proteostasis in the aged and Alzheimer’s disease brain - John Newman, MD, PhD, Buck Institute of Aging
    • Medium-chain triglycerides improve cognition and systemic metabolism in mouse models of Alzheimer’s disease - Karl Fernandes, PhD, University of Sherbrooke
    • ApoE4 impairs astrocytic lipid droplet formation via endolysosomal dysfunction - Maria Ioannou, PhD, University of Alberta
    		  
     10:30 - 11:00 Refreshment Break & Poster Viewing  
     11:00 - 12:30 SMALL GROUP DISCUSSIONS: Topics suggested from the attendees  
     12:30 - 14:00 Lunch Break  
     14:00 - 15:30

    SYMPOSIUM 7: The Glia-Neuron Gossip: Secrets of Cellular Communication

    Chairs: Maya Kaelberer, PhD & Alexander Mascarenhas, student

    • Metabolic interactions between astroglial CB1R receptors, the lactate receptor HCA1R and serine: Who’s in control? - Ignacio Fernandez-Moncada, PhD, INSERM
    • Abeta increases astrocyte IDO1 to restore lactate production - Katrin Andreasson, PhD, Stanford University
    • Adenosine signaling to astrocytes coordinates brain metabolism and function - Alexander Gourine, PhD, University College of London
    		  
     15:30 - 16:00 Refreshment Break & Poster viewing
    		  
     16:00 - 17:30

    SYMPOSIUM 8: Targeting Bioenergetics in the Aging Neuron

    Chairs: Robert Zorec, PhD & Isaura Maria Suarez Uribe, student

    • Mitochondrial dysfunction in astrocytes: Linking neurodegeneration and systemic metabolic imbalance - Eduardo Balsa, PhD, Universidad Autónoma de Madrid
    • Boosting neuronal activity-driven mitochondrial DNA transcription improves cognition in aged mice - Huan Ma, PhD, Zhejiang University, China
    • Neurovascular function in mouse models of mixed disease (AD and atherosclerosis) - Clare Howarth, PhD, University of Sheffield
    		  
     17:30 - 17:45 Quick break to remove posters  
     17:45 - 18:30

    SYMPOSIUM 9: Interactive Discussion on key and/or emerging areas that need more research

    Facilitators: Ray Swanson, Caroline Lindy Rae, and Joao Duarte

    		  
     18:30 - 19:00

    SPECIAL SESSION

    Chair: Mary McKenna, PhD

    • Presentation of awards for best student short talks and student/postdoc posters - Mary McKenna, PhD
    • Meeting wrap up & closing comments - Jordi Duran, PhD
    		  
    19:00 -  22:00 FAREWELL DINNER  

    FRIDAY, JULY 3

    7:00 - 8:00 AM Breakfast at your hotel


    8:00 - 5:00 PM ONE-ON-ONE NETWORKING OPPORTUNITIES   

    Optional informal networking events offer young scientists the opportunity to engage in discussions and consultations with senior scientists and other meeting participants. It's a chance to discuss their research, explore potential collaborations, or seek advice from more experienced scientists. 

    ICBEM is a registered FL non-profit organization.

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